Guard Column Starter Set, Diamond Hydride 2.o, complete with 5 each 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.

Additional Info:

Diamond Hydride™ 2.o Guard Column Starter Set for Reliable Method Protection

The 70200‑PG1 Diamond Hydride™ 2.o Guard Column Starter Set provides a complete, ready‑to‑use solution for protecting high‑efficiency analytical HPLC columns. Designed around Cogent TYPE‑C™ silica hydride technology, this starter set helps preserve column performance, maintain consistent retention, and extend analytical column lifetime in routine and advanced HILIC workflows.

Guard columns are especially important when working with 2.2 µm particle analytical phases, where particulate contamination and strongly retained sample components can quickly degrade performance.

What’s Included

This comprehensive starter set includes all required components for immediate implementation:

  • Stainless Steel Guard Cartridge Column Holder Precision‑manufactured to ensure secure, low‑dead‑volume installation upstream of the analytical column.

  • Five Diamond Hydride™ 2.o Guard Cartridges Each cartridge is packed with 2.2 µm, 120 Å Diamond Hydride™ stationary phase, closely matched to analytical Diamond Hydride 2.o columns to maintain consistent selectivity and retention behavior.

Each guard cartridge is shipped in an individual, closeable Delrin® storage case to prevent drying, contamination, or handling damage prior to installation.

Why Diamond Hydride™ 2.o Guard Columns Are Recommended

Using a matched guard column provides several important benefits:

  • Protects analytical columns from particulates and irreversibly retained matrix components

  • Preserves peak shape, retention stability, and column efficiency

  • Extends analytical column lifetime and reduces replacement costs

  • Improves method reproducibility over extended analytical sequences

Under average laboratory use conditions, the included cartridges are often sufficient to protect an analytical column for the majority of its service life.

Diamond Hydride™ 2.o Stationary Phase Consistency

The guard cartridges are packed with the same Diamond Hydride™ 2.o stationary phase used in analytical columns, ensuring:

  • No change in selectivity or elution order

  • Minimal additional dead volume

  • Seamless integration into existing HILIC methods

  • Stable retention under high‑organic mobile‑phase conditions

The silica hydride surface supports mixed‑mode interactions, providing effective protection across a broad range of polar analytes.

Compatibility

The 70200‑PG1 Guard Column Starter Set is designed for use with:

  • 2.1 mm ID analytical columns

  • Diamond Hydride™ 2.o HPLC and LC‑MS methods

  • Conventional HPLC and UHPLC systems capable of stable low‑flow operation

The guard holder and cartridges install directly upstream of the analytical column for maximum effectiveness.

Replacement and Use Guidance

Guard cartridges should be replaced when:

  • System backpressure increases noticeably

  • Peak shape or retention behavior begins to change

  • Sample load, cleanliness, or matrix complexity increases

Routine replacement ensures continued protection and consistent analytical performance.

 

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